Table II.
Analysis of genetic resistance to macrolides and doxycycline in the population
| Syphilis stage | Resistance gene | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| rRNA 23S | rRNA 16S | |||||||||
| PCR n (%) | Seq n (%) | Macrolide-sensitive n (%) | Macrolide-resistant (A2058G) n (%) | PCR n (%) | Seq n (%) | Doxycycline-resistant | ||||
| (926–928) | –939 | (965–967) | –1058 | |||||||
| All stages | 104 (71) | 104 (100) | 16 (15.4) | 88 (85) | 130 (89) | 127 (98) | 0 | 0 | 0 | 0 |
| Primary (n = 93) | 70 (75.3) | 70 (100) | 9 (12.8) | 61 (87.1) | 85 (91.3) | 82 (96.5) | 0 | 0 | 0 | 0 |
| Secondary (n = 53) | 34 (64.1) | 34 (100) | 7 (20.6) | 27 (79.4) | 45 (85) | 45 (100) | 0 | 0 | 0 | 0 |