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Difference in the measurement of gray matter volume. In VBM (left), volume was calculated from voxel size and signal intensity on a segmented gray matter image used as a tissue probability map. In SBM (right), volume was calculated from area size and gray matter thickness. Gray matter thickness is defined as the distance between the pial and white matter surfaces. SBM, surface-based morphometry; VBM, voxel-based morphometry.
