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. 2022 Feb 18;21(1):41–57. doi: 10.2463/mrms.rev.2021-0096

Table 1.

Popular software packages in voxel- and surface-based morphometry

Package name Type Spatial normalization method Platform URL
SPM VBM DARTEL Tool MATLAB https://www.fil.ion.ucl.ac.uk/spm/software/
FSL VBM FLIRT and FNIRT Apple, Linux, and Windows (Windows via a Virtual Machine) https://fmrib.ox.ac.uk/fsl/
FreeSurfer SBM Spherical map registration51 Apple, Linux, and Windows (Windows via a Virtual Machine) https://surfer.nmr.mgh.harvard.edu/
CIVET SBM Robbins’s method49 Linux and web-based platform https://mcin.ca/technology/civet/
CAT12 SBM Geodesic Shooting50 MATLAB www.neuro.uni-jena.de/cat/

CAT12, computational anatomy toolbox 12; FSL, FMRIB software library; SBM, surface-based morphometry; SPM, statistical parametric mapping; VBM, voxel-based morphometry.