Table 1. Quantitative model of germline tra-2 activity.

T represents the activity of one wild-type tra-2 locus without trans-acting repression. H, F, and G represent factors (ranging from 0–1) that adjust T downward in response to the HA epitope tag of tra-2(nm75), activity of fog-2(+), or activity of gld-1(+), respectively. E represents a factor (>1) by which T is increased in the tra-2(e2020) dominant Fog allele. Because reduction of gld-1 and fog-2 function impact sexual fate independently and in e2020 mutants (see Tables 2 and 3), F and G are retained as factors even when combined with tra-2(e2020) alleles.

Genotype	Germline phenotype	tra-2 activity	value for F=G=H=0.5 E>2
Wild-type	Hermaphrodite	2TFG	T/2
tra-2(null)/+	Hermaphroditea	TFG	T/4
tra-2:HA	Hermaphroditeb	2TFGH	T/4
tra-2(null)/+; fog-2(null)	Hermaphroditec	TG	T/2
tra-2:HA; fog-2(null)	Hermaphroditeb	2TGH	T/2
tra-2:HA/+; fog-2(null)	Fogb	TG+TGH	3T/4
fog-2(null)	Fogc	2TG	T
gld-1(null)	Fog (Tum)d	2TF	T
tra-2(e2020)/+	Foge	TEFG+TFG	>3T/4
tra-2(e2020)/tra-2(null)	Foge	TEFG	>T/2
tra-2(null)	Moga	0	0

^a Hodgkin and Brenner (1977)

^bThis study

^c Schedl and Kimble (1988)

^d Francis et al. (1995a)

^e Doniach (1986)