Table 2.

Selected Drug Enforcement Administration Reports, United States

First Author, Year (Reference No.)	Design	Primary Outcome	Key Findings
Harm Reduction Ohio, 2019 (23)	Serial cross-sectional analysis of crime laboratory data from Ohio Bureau of Criminal Investigation in 2018	Association between risk of fentanyl contamination and size of cocaine package	Cocaine confiscations of 100 g or more were free of fentanyl. Three midsize packages of 99, 85, and 35 g were positive for fentanyl. The presence of fentanyl continued to increase as the size of package decreased, and 14.1% of cocaine packets less than one-tenth of a gram contained fentanyl.
DEA, National Drug Threat Assessment, 2019 (17)	Integration of reporting from law enforcement, intelligence, and public health agencies	Assessment of threat posed by domestic and international drug trafficking	Cocaine: Availability is increasing, along with export quality. Price has seen an overall decrease from 2012–2018. Treatment Episode Data Set shows that admissions for treatment have declined over 78%. Methamphetamine: Price has decreased, while potency has increased, indicating increased availability.
DEA Bulletin, 2018 (21)	Analysis of seized cocaine in Florida from 2016–2017	Contamination of cocaine in Florida	Cocaine and fentanyl combination found in 180 exhibits of cocaine in Florida, although the number of cocaine exhibits without fentanyl was unclear. Report also cites Florida’s Medical Examiners Commission as reporting that 2,499 of the 2,882 state cocaine deaths involved cocaine in combination with another drug.
DEA Bulletin, 2018 (22)	Analysis of seized cocaine in Pennsylvania from 2015–2017	Contamination of cocaine in Pennsylvania	Analysis of 30,914 cocaine exhibits. Noted a 112% increase from 2016 to 2017 of 63 to 134 exhibits.

Abbreviation: DEA, Drug Enforcement Administration.