TABLE 3.
Density of steroid receptors in the SCN.
| Receptor | Species | Sex | Age | Intensity | Localization | Assay | References |
| AR | Human | M | Adult | ++ | ? | IHC | Kruijver and Swaab, 2002 |
| F | Adult | + | ? | IHC | |||
| Rat | M | Adult | + | Shell | IHC | Jahan et al., 2015 | |
| Mouse | M | Adult | +++ | Core | IHC | Wang et al., 2007 | |
| F | Adult | + | Core | IHC, WB | Iwahana et al., 2008 | ||
| Ferret | M | Adult | +++ | Homogeneous | IHC | Kashon et al., 1996 | |
| Baboon | F | Fetal | ++ | ? | Autoradiography | Handa et al., 1988 | |
| M+F | Fetal | + | ? | IHC | Wu et al., 1995 | ||
| Goat | M | Adult | +++ | ? | IHC | Maejima et al., 2009 | |
| ERα | Human | M | Adult | ++ | ? | IHC | Kruijver and Swaab, 2002 |
| F | Adult | +++ | ? | IHC | |||
| Mouse | ORCHX M | Adult | + | Shell | Vida et al., 2008 | ||
| OVX F | Adult | ++ | Shell | ||||
| Rats | OVX F | Adult | − | ? | ISH | Shughrue et al., 1997b | |
| M+F | PND0 | + | N/A | ICC | Su et al., 2001 | ||
| Plains vizcacha | F | Adult | ++ | ? | IHC | Inserra et al., 2017 | |
| ERβ | Human | M | Adult | + | ? | IHC | Kruijver and Swaab, 2002 |
| F | Adult | ++ | ? | IHC | |||
| Mouse | ORCHX M | Adult | + | Shell | IHC | Vida et al., 2008 | |
| OVX F | Adult | +++ | Shell | IHC | |||
| Rats | OVX F | Adult | + | ? | ISH | Shughrue et al., 1997b | |
| M+F | PND0-19 | + | ? | ISH | Cao et al., 2014 | ||
| M+F | PND0 | ++ | N/A | ICC | Su et al., 2001 | ||
| Sheep | M | Adult | + | ? | ISH | Hileman et al., 1999 | |
| PR | Human | M | Adult | ++ | ? | IHC | Kruijver and Swaab, 2002 |
| F | Adult | ++ | ? | IHC | |||
| Rats | M | Adult | − | N/A | IHC | Auger and De Vries, 2002 | |
| Ginea pigs | F | Adult | − | N/A | IHC | Blaustein et al., 1988 | |
| Rabbits | F | Adult | − | N/A | IHC | Caba et al., 2003 | |
| Japanese macaques | F | Pubertal | − | N/A | IHC | Goldsmith et al., 1997 | |
| Crab-eating macaques | M+F | Adult+ pubertal | − | N/A | IHC | Bethea et al., 1992 | |
| GR | Mouse | ? | Adult | – | N/A | ISH | Balsalobre et al., 2000 |
| Rats | M | PND2 | +++ | ? | IHC | Rosenfeld et al., 1988 | |
| PND8 | +++ | ||||||
| PND12 | ++ | ||||||
| PND16 | ++ | ||||||
| PND20 | + | ||||||
| Adult | + | ||||||
| M | Adult | + | ? | IHC | Ahima and Harlan, 1990 | ||
| M | Adult | + | ? | IHC | Cintra et al., 1994b | ||
| M | Adult | + | ? | ISH | Su et al., 2015 | ||
| MR | Rats | M | Adult | + | ? | IHC | Ahima et al., 1991 |
| M | Adult | + | ? | ISH | Su et al., 2015 |
AR, androgen receptors; ER, estrogen receptor; F, female; GR, glucocorticoid receptor; ICC, immunocytochemictry; IHC, immunohistochemistry; ISH, in situ hybridization; M, male; MR, mineralocorticoid receptor; N/A, not applicable; ORCHX, orchidectomized; OVX, ovariectomized; PND, postnatal day; WD, western blot; ?, not reported; −, not detected; +, weak expression; ++, intermediate expression; +++, strong expression.