Fig. 6. Cold-catalytic antitumor immunity with BP nanosheets in vivo. (A) Schedule for the detection of in vivo immune activation. (B) Flow cytometry analysis of dendritic cell (DC) maturation. (C) Matured dendritic cells (CD80highCD86high) were calculated according to flow cytometry. (D) and (E) Intratumoral activation of cytotoxic T lymphocytes (CTLs) and T helper (Th) cells in distant tumors. (F) Serum INF-γ was detected after different treatments. Groups: (1) PBS, (2) ΔT, (3) BP nanosheets, and (4) BP nanosheets + ΔT. The data were presented as mean ± SD (n = 5, **p < 0.01).
