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. 2022 May 10;13(23):6982–6989. doi: 10.1039/d2sc01621d

Evaluation of the benzoate ester structurea.

graphic file with name d2sc01621d-u1.jpg
a

Reaction conditions: 1–8 (0.1 mmol), 9 (0.15 mmol), Hantzsch ester (0.2 mmol), NaOAc (0.2 mmol) in DMSO (0.05 M) at rt for 17 h.

b

NMR yields using 1,1,2,2-tetrachloroethane as the internal standard.

c

In brackets isolated yield on 0.2 mmol scale.