Evaluation of the benzoate ester structurea.
Reaction conditions: 1–8 (0.1 mmol), 9 (0.15 mmol), Hantzsch ester (0.2 mmol), NaOAc (0.2 mmol) in DMSO (0.05 M) at rt for 17 h.
NMR yields using 1,1,2,2-tetrachloroethane as the internal standard.
In brackets isolated yield on 0.2 mmol scale.