Table 1.
Comparison of Nugent Score and Vaginal Microbiota Across All Populations of Women at Baseline
| Characteristic | Adolescent Females (n = 93) |
Postmenopausal Women (n = 86) |
Lactating Women (n = 16) |
P Value |
|---|---|---|---|---|
| Nugent score | <.001 | |||
| Normal | 51 (54.8) | 23 (26.7) | 6 (37.5) | |
| Intermediate | 15 (16.1) | 44 (51.2) | 4 (25.0) | |
| Bacterial vaginosis | 27 (29.0) | 19 (22.1) | 6 (37.5) | |
| Organism prevalence | ||||
| Lactobacillus crispatus | 33 (35.5) | 22 (25.6) | 2 (12.5) | .12 |
| Lactobacillus iners | 74 (79.6) | 37 (43.0) | 7 (43.8) | <.001 |
| Lactobacillus jensenii | 37 (39.8) | 19 (22.1) | 3 (18.8) | .025 |
| Lactobacillus gasseri | 31 (33.3) | 21 (24.4) | 5 (31.3) | .435 |
| Limosilactobacillus vaginalis | 32 (34.4) | 15 (17.7) | 2 (12.5) | .018 |
| Gardnerella vaginalis | 68 (73.1) | 49 (57.0) | 11 (68.8) | .072 |
| Atopobium vaginae | 44 (47.3) | 27 (31.4) | 6 (37.5) | .089 |
| Megasphaera lornae | 23 (24.7) | 10 (11.6) | 1 (6.3) | .039 |
| Prevotella bivia | 36 (38.7) | 21 (24.4) | 3 (18.8) | .077 |
| Prevotella amnii | 17 (18.3) | 6 (7.0) | 1 (6.3) | .056 |
| Prevotella timonensis | 56 (60.2) | 38 (44.2) | 6 (37.5) | .051 |
| Enterococcus faecalis | 25 (26.9) | 18 (20.9) | 2 (12.5) | .434 |
| Group B Streptococcus | 17 (18.3) | 7 (8.1) | 1 (6.3) | .106 |
| Staphylococcus aureus | 7 (7.5) | 1 (1.2) | 0 | .097 |
| Escherichia coli | 19 (20.4) | 19 (22.1) | 1 (6.3) | .357 |
| Candida albicans | 23 (24.7) | 2 (2.3) | 2 (12.5) | <.001 |
| Non-albicans yeast | 0 | 3 (3.5) | 0 | .207 |
Data are presented as No. (%) unless otherwise indicated. Bold values indicate significant differences between populations at baseline.