Figure 6.

Effect of MYR on the expression levels of brain-derived neurotrophic factor (BDNF) and tropomyosin-related kinase B (TrkB) mRNAs in rats hippocampal with SPS-induced depression- and anxiety-like behaviors (a). The relative intensities of polymerase chain reaction amplification product bands on agarose gels are shown. The expression levels of BDNF and TrkB mRNAs were normalized to the expression level of glyceraldehyde 3-phosphate dehydrogenase mRNA as an internal control. Activation of phosphor-extracellular signal-regulated kinase (p-ERK) in the hippocampus after MYR treatment (b). Western blot analysis of protein expression levels of p-ERK. ^∗p<0.05 and ^∗∗p<0.01 vs. SAL group; ^#p<0.05 vs. SPS group.