Table 3.
Comparative analysis of immunological, inflammatory markers, and hematological and clinical biochemical characteristics between two groups of total severe patients with and without O2 requirement.
| Parameter | Total COVID-19 patients (No. = 88) | ∗ p≤∗ | |
|---|---|---|---|
| Severe patients (pneumonia with O2 requirement) | Severe patients (pneumonia without O2 requirement) | ||
| No of patients | 54 (61%) | 34 (39%) | — |
| Sex, F/M | 14/40 | 14/20 | 0.02 |
| Age (years) | 43.6 ± 8.82 | 45.70 ± 13.09 | NS |
| Range | (34–72) | (34–68) | |
| WBC (109/L) | 14.51 ± 5.70 | 12.15 ± 4.86 | 0.04 |
| Lym (109/L) | 0.544 ± 0.02 | 1.72 ± 0.11 | 0.0001 |
| Neu (109/L) | 12.27 ± 0.82 | 9.86 ± 0.69 | 0.04 |
| Mon (109/L) | 0.59 ± 0.04 | 0.97 ± 0.07 | 0.0001 |
| RBC (1012/L) | 3.93 ± 0.6 | 4.59 ± 1.1 | NS |
| Hb (g/dl) | 10.94 ± 2.59 | 11.15 ± 1.43 | NS |
| ESR (mm/h) | 55.59 ± 14.19 | 44.11 ± 11.85 | 0.03 |
| Hs-CRP (mg/L) | 46.29 ± 5.71 | 37.70 ± 3.23 | 0.009 |
| IL-6 (pg/ml) | 911.97 ± 40.94 | 271.19 ± 16.75 | 0.0001 |
| LDH (U/L) | 713.50 ± 51.53 | 607.11 ± 45.79 | NS |
| Ferritin (ng/ml) | 1010.64 ± 101.96 | 976.29 ± 95.93 | NS |
| ALT (U/L) | 35.84 ± 5.34 | 28.51 ± 3.61 | 0.02 |
| AST (U/L) | 35.48 ± 2.29 | 40.20 ± 4.10 | NS |
| Creatinine (mg/dl) | 1.45 ± 0.37 | 0.740 ± 0.07 | 0.01 |
| Urea (mg/dl) | 76.85 ± 7.41 | 48.20 ± 4.75 | 0.006 |
| Albumin (g/dl) | 3.40 ± 0.50 | 3.33 ± 0.41 | NS |
| Direct bilirubin (mg/dl) | 0.18 ± 0.01 | 0.20 ± 0.03 | NS |
| Total bilirubin (mg/dl) | 0.67 ± 0.04 | 0.55 ± 0.05 | NS |
| Glucose (g/dl) | 241.49 ± 16.27 | 178.36 ± 18.29 | 0.01 |
| D-dimer (ng/ml) | 2.13 ± 0.07 | 3.51 ± 0.70 | 0.01 |
| APTT (sec) | 29.0 ± 9.22 | 27.41 ± 1.70 | NS |
| Troponin T (ng/ml) | Negative | Negative | |
∗ p denotes statistical significance at the 0.05 level. Data are presented as mean ± standard deviation (range).