Fig. 3. Anti-Müllerian hormone receptor II (AMHR2)-extracellular domain (ED) vaccination using AddaVax as adjuvant is highly effective in preventing the growth of mouse epithelial ovarian carcinomas (EOCs). Prophylactic AMHR2-ED vaccination of mouse ovarian carcinoma (MOVCAR) inoculated TgMISIIR-Tag (low) female mice using complete Freund’s adjuvant (CFA) as adjuvant resulted in (A) significant inhibition of MOVCAR tumor growth and (B) significant enhancement of overall survival. Likewise, prophylactic AMHR2-ED vaccination of MOVCAR inoculated TgMISIIR-Tag (low) female mice using AddaVax as adjuvant resulted in (C) significant inhibition of MOVCAR tumor growth and (D) significant enhancement of overall survival. Error bars indicate ±standard deviation and asterisks indicate significance.