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. Author manuscript; available in PMC: 2023 Jul 1.
Published in final edited form as: Biol Psychiatry. 2021 Dec 16;92(1):25–33. doi: 10.1016/j.biopsych.2021.11.025

Figure 3. Heatmaps for associations between AD features and the brain transcripts and proteins regulated by the depression-associated SNPs.

Figure 3.

(A) For the 46 transcripts (y-axis) associated with AD-related traits (x-axis) in ROS/MAP samples. (B) For seven proteins (y-axis) in ROS/MAP samples associated with AD-related traits (x-axis). (C) For eight proteins (y-axis) in Banner samples associated with AD-related traits (x-axis). The asterisk depicts the FDR p < 0.05. (D) For seven proteins (y-axis) that replicated in both the discovery and replication analyses after a meta-analysis. The asterisk represents. The color reflects the direction of the association of expression levels with each AD-related trait.