Table 4.
Age (years) | Mean | SD |
---|---|---|
49.3 | 15.5 | |
Tumor size (mm) | Mean | SD |
17.8 | 9.7 | |
Gender | N | Percent |
F | 11 | 42% |
M | 15 | 58% |
Medial walls resected | N | Percent |
21/26 | 81% | |
IGF-1 levels | Mean | SD |
Preoperative | 701.5 | 201.9 |
Postoperative | 194.6 | 54.7 |
Growth hormone levels | Mean | SD |
Postoperative | 0.96 | 0.8 |
WHO 2017 adenoma classification | N | Percent |
Densely granulated | 4 | 16% |
Sparsely granulated | 10 | 42% |
Mixed somatolactotroph | 7 | 23% |
Mammosomatotroph | 2 | 6% |
Plurihormonal | 3 | 12% |
Knosp grade | N | Percent |
Grade 0 | 6 | 23% |
Grade 1 | 12 | 46% |
Grade 2 | 4 | 15% |
Grade 3A | 0 | 0% |
Grade 3B | 2 | 8% |
Grade 4 | 2 | 8% |
Remission rates | N | Percent |
Biochemical remission (Surgery) | 23/25 | 92% |
Biochemical remission (Surgery + Adjuvant) | 2/25 | 8% |
Biochemical remission of entire case series | 25/25 | 100% |
Cohort of 26 consecutive newly diagnosed acromegaly patients. Variables include age, tumor size, gender, initial presentation, number of medial walls resected, postoperative growth hormone levels, preoperative and postoperative IGF-1 levels, WHO 2017 Adenoma subtype classification, Knosp grade and remission rates. Categorical variables are reported as number and percentage, and continuous variables are reported as mean ± standard deviation.