. 2022 Jun 2;13:791229. doi: 10.3389/fendo.2022.791229

Table 3.

Risks of adverse perinatal outcomes within different causes of infertility.

Outcomes	Fertile NC		Infertile NC		Tubal factor ART		Ovulatory dysfunction ART		Endometriosis ART		Unexplained infertility ART
	%	AOR (95% CI)	%	AOR (95% CI)	%	AOR (95% CI)	%	AOR (95% CI)	%	AOR (95% CI)	%	AOR (95% CI)
PTB	4.0	Ref	6.4	1.64 (0.84, 3.20)	6.2^a	1.49 (1.12, 2.00) ^b	7.9^a	1.87 (1.29, 2.72) ^b	5.7	1.44 (0.56, 3.71)	7.8^a	1.88 (1.11, 3.17) ^b
PTB	4.0	–	6.4	Ref	6.2^a	0.91 (0.49, 1.70)	7.9^a	1.15 (0.59, 2.26)	5.7	0.87 (0.29, 2.62)	7.8^a	1.15 (0.53, 2.46)
LBW	3.2	Ref	2.8	0.84 (0.33, 2.15)	3.3	0.91 (0.65, 1.27)	4.2	1.16 (0.73, 1.83)	1.1	0.31 (0.04, 2.29)	3.7	0.99 (0.49, 2.01)
LBW	3.2	–	2.8	Ref	3.3	1.07 (0.43, 2.65)	4.2	1.37 (0.52, 3.58)	1.1	0.36 (0.04, 3.19)	3.7	1.17 (0.39, 3.50)
SGA	4.6	Ref	1.7	0.40 (0.12, 1.28)	4.0	0.82 (0.62, 1.10)	2.7^a	0.53 (0.31, 0.89) ^b	5.7	1.21 (0.47, 3.12)	2.2	0.44 (0.19, 1.04)
SGA	4.6	–	1.7	Ref	4.0	2.08 (0.66, 6.58)	2.7^a	1.33 (0.39, 4.57)	5.7	3.04 (0.70, 13.13)	2.2	1.11 (0.27, 4.52)
LGA	20.9	Ref	22.0	1.11 (0.75, 1.64)	24.3^a	1.28 (1.11, 1.48) ^b	25.9^a	1.27 (1.03, 1.57) ^b	23.0	1.30 (0.77, 2.20)	21.6	1.06 (0.77, 1.47)
LGA	20.9	–	22.0	Ref	24.3^a	1.15 (0.79, 1.67)	25.9^a	1.13 (0.76, 1.70)	23.0	1.17 (0.63, 2.19)	21.6	0.96 (0.60, 1.53)

Models adjusted for maternal age, maternal BMI, maternal PIH, and maternal GDM.

aOR, adjusted odds ratio; CI, confidence intervals; NC, naturally conceived; ART, assisted reproductive technology; PTB, preterm birth; LBW, low birth weight; SGA, small for gestational age; LGA, large for gestational age.

^aAdjusted P value <0.05 for the comparison with the fertile NC group.

^baOR showed significant difference.