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. 2022 Jun 2;9:829033. doi: 10.3389/fmed.2022.829033

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Copyright © 2022 Liu, Xiao, Xia, Huang, Chen, Xu, Chen, Wang, Wei, Li, Shu, Lu, Zhang and He.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Consistency between organoid and patient responses to different drugs. (A) Timetable of disease progression. (B) Drug sensitivity data indicating low sensitivities to 5-fu and oxaliplatin and high sensitivities to apatinib and SN38. (C) Representative CT images of heart diaphragm angle lymph node after treatment. (D) Sum of the length and width of heart diaphragm angle lymph node after treatment with XELOX, FORFIRI, and FORFIRI and apatinib, red bars indicate volume of the target metastasis [according to RECIST 1.1].