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. 2022 Jun 2;16:861136. doi: 10.3389/fnhum.2022.861136

TABLE 2.

Group differences in gait features between DMD at baseline and TD, and results from MWU-test.

Median (Q1-Q3)
MWU-test
Variables DMD TD BH corrected p-value
Cadence (steps/s) 2.25 (2.01–2.40) 2.21 (1.97–2.47) 0.4639
WVnorm (/) 0.40 (0.37–0.43) 0.46 (0.43–0.51) 0.0036*
SWnorm (/) 0.28 (0.24–0.30) 0.16 (0.11–0.19) 0.0036*
SLnorm (/) 0.74 (0.70–0.79) 0.77 (0.74–0.85) 0.0281*
Gait profile score (°) 6.81 (5.13–8.37) 5.21 (4.87–6.57) 0.0924
Max anterior pelvic tilt (°) 16.36 (14.30–19.03) 11.64 (8.69–15.26) 0.0047*
ROM pelvic obliquity (°) 9.62 (7.50–13.32) 7.42 (6.97–9.20) 0.0502
ROM pelvic rotation (°) 14.41 (9.96–17.18) 14.93 (11.21–17.49) 0.7535
Min hip flex angle stance (°) −3.08 (−7.68 to 3.77) −10.13 (−13.32 to −6.84) 0.0006*
Max hip flex angle swing (°) 41.81 (34.67–49.01) 34.12 (29.19–37.89) 0.0018*
ROM hip sagittal plane (°) 42.70 (38.90–46.95) 45.42 (41.02–47.77) 0.2578
Max hip ext mom stance (Nm/kg) 0.507 (0.388–0.688) 1.098 (0.699–1.319) 0.0012*
Min hip ext mom stance (Nm/kg) −0.698 (−0.789 to −0.516) −0.904 (−1.068 to −0.772) 0.0009*
Max hip power stance (W/kg) 0.440 (0.334–0.775) 0.665 (0.445–1.094) 0.0554
Min hip add angle stance (°) −6.79 (−8.36 to −3.96) −4.92 (−6.29 to −2.92) 0.0501
Min hip add angle swing (°) −9.45 (−11.38 to −8.03) −6.50 (−7.14 to −5.34) 0.0018*
Max hip abd mom stance (Nm/kg) 0.559 (0.443–0.735) 0.648 (0.581–0.723) 0.0582
Max knee flex angle stance (°) 35.02 (33.16–39.36) 35.55 (28.03–40.28) 0.7722
Min knee flex angle stance (°) 9.06 (3.86–12.31) 3.65 (−2.54–7.62) 0.0070*
ROM knee sagittal plane stance (°) 28.01 (24.31–30.70) 30.72 (28.06–33.23) 0.0070*
Max knee flex angle swing (°) 69.48 (64.38–74.45) 64.75 (60.05–67.84) 0.0038*
Max knee ext mom stance (Nm/kg) 0.414 (0.337–0.490) 0.512 (0.325–0.663) 0.1263
Min knee ext mom stance (Nm/kg) −0.049 (−0.120 to 0.022) −0.207 (−0.334 to −0.157) 0.0007*
Dorsiflex angle IC (°) 0.80 (−3.61 to 4.07) 0.77 (−1.70 to 3.77) 0.9586
Max dorsiflex angle stance (°) 15.09 (11.34–17.20) 12.53 (9.47–16.55) 0.3147
Max dorsiflex angle swing (°) 5.31 (0.02–6.95) 5.27 (2.56–8.35) 0.4202
Min plantar flex mom LR (Nm/kg) −0.050 (−0.088 to −0.008) −0.127 (−0.184 to −0.069) 0.0012*
Max plantar flex mom PO (Nm/kg) 0.976 (0.864–1.185) 1.318 (1.141–1.446) 0.0009*
Min ankle power LR (W/kg) −0.501 (−0.941 to −0.265) −0.467 (−0.605 to −0.349) 0.9128
Max ankle power PO (W/kg) 3.022 (2.271–3.384) 3.973 (3.100–4.386) 0.0020*
Max int foot prog angle stance (°) −7.96 (−11.96 to −3.13) 0.11 (−4.16 to 4.22) 0.0005*

The asterisks (*) indicate significance level at BH corrected p-value < 0.05. abd, abduction; add, adduction; BH, Benjamini-Hochberg procedure; DMD, Duchenne muscular dystrophy; dorsiflex, dorsiflexion; ext, extension; flex, flexion; IC, initial contact; int, internal; LR, loading response; Max, maximal; Min, minimal; mom, moment; MWU, Mann-Whitney U; PO, push-off; prog, progression; ROM, range of motion; SLnorm, normalized step length; SWnorm, normalized step width; TD, typically developing; WVnorm, normalized walking velocity.