Figure 4.

Chemokine levels in human plasma after treatment with B. jararaca venom. Human blood samples containing GPRP (8 mg/mL) were incubated with increasing concentrations of B. jararaca venom or sterile saline solution for 30, 60 and 120 minutes at 37°C. After plasma collection and dilution (1:2), the presence of chemokines was evaluated by cytometric bead array (CBA). The results are represented as the mean ± SEM of duplicates from three independent tests. ns, not significant; *p ≤ 0.05, **p ≤ 0.005, ***p ≤ 0.0005, ****p < 0.0001.