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. 2022 May;10(10):544. doi: 10.21037/atm-22-1946

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2022 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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GFAT1⁺ PC cells have higher invasive and migratory potential in vitro. (A,B) GFAT1⁻ and GFAT1⁺ cells from both cell lines were analyzed in a cell invasion assay, as shown by quantification (A) and by representative images (B). (C,D) GFAT1⁻ and GFAT1⁺ cells from both cell lines were analyzed in a cell migration assay, as shown by quantification (C) and by representative images (D). Cells in (B) and (D) were stained with Giemsa. *, P<0.05. N=5. Scale bars are 100 µm. GFAT1, glutamine-fructose-6-phosphate transaminase 1; PC, pancreatic cancer.