Table 2. Results of the hemodynamic changes analysis in different groups of rats (n=6, mean ± SD).
| Indexes | O2 | Control | AZ | Rh | AZ + Rh | F | P |
|---|---|---|---|---|---|---|---|
| CVP (mmHg) | 20% O2 | 4.3±0.2 | 4.3±0.3 | 4.1±0.3 | 4.0±0.4 | 1.23 | 0.32 |
| 15% O2 | 4.4±0.2 | 4.2±0.4 | 4.2±0.2 | 3.9±0.2* | 4.25 | 0.02 | |
| MAP (mmHg) | 20% O2 | 97.8±4.1 | 96.1±3.2 | 96.7±3.4 | 96.4±3.6 | 0.30 | 0.82 |
| 15% O2 | 92.3±3.9# | 94.6±3.5 | 95.1±4.1 | 96.1±3.3 | 1.31 | 0.29 | |
| PAP (mmHg) | 20% O2 | 37.2±2.0 | 36.9±2.0 | 37.3±2.4 | 37.1±2.5 | 0.04 | 0.98 |
| 15% O2 | 39.9±2.5# | 37.8±2.5 | 37.9±0.35 | 37.3±0.03* | 2.91 | 0.05 | |
| LAP (mmHg) | 20% O2 | 2.5±0.2 | 2.4±0.1 | 2.5±0.3 | 2.3±0.2 | 1.43 | 0.26 |
| 15% O2 | 2.7±0.1# | 2.5±0.1* | 2.6±0.3 | 2.4±0.1* | 3.89 | 0.02 | |
| ABF (mL·min-1) | 20% O2 | 32.1±1.3 | 31.2±1.1 | 31.4±1.4 | 31.6±1.5 | 0.58 | 0.62 |
| 15% O2 | 27.7±1.2# | 30.1±1.2* | 29.8±1.2 | 30.7±1.3* | 6.72 | <0.01 | |
| Paw (cmH2O) | 20% O2 | 10.7±0.6 | 10.2±0.4 | 10.6±0.3 | 10.4±0.5 | 1.60 | 0.21 |
| 15% O2 | 11.0±0.5 | 10.6±0.3 | 11.2±0.5 | 10.9±0.6 | 1.19 | 0.33 | |
| HR (bpm) | 20% O2 | 331±20.8 | 312±18.6 | 325±20.5 | 309±19.8 | 1.93 | 0.15 |
| 15% O2 | 334±19.3 | 323±17.4 | 330±18.1 | 316±19.2 | 1.28 | 0.3 |
*, vs. Control, P≤0.05; #, vs. Control 20% O2, P<0.05. AZ, acetazolamide; Rh, Rhodiola; CVP, central venous pressure; MAP, mean arterial pressure; PAP, pulmonary artery pressure; LAP, left atrial pressure; ABF, ascending aortic blood flow; Paw, airway pressure; HR, heart rate.