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. 2022 Jun 2;13:902065. doi: 10.3389/fphar.2022.902065

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Copyright © 2022 Chen, Xin, Xu, Zhao and Lv.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Hemodynamic measurements. In the RR group, SBP was significantly decreased from T2 to T8 except at T5, while DBP was significantly increased at T7 and T8 (p < 0.05). RespR was significantly increased at T3 and T7, while HR was significantly increased at T8 and T9 in the RR group (p < 0.05). SpO2 was significantly increased from T4 to T7 except at T5 in the RR group (p < 0.05). Abbreviations DBP, diastolic blood pressure; HR, heart rate; RespR, respiratory rate; RR, remimazolam tosilate-remifentanil (RT-RF); SBP, systolic blood pressure; SpO2, oxygen saturation. Time metrics are as follows: T2, immediately before start of procedure; T3, 3 min after start of procedure; T4, 6 min after start of procedure; T5, 9 min after start of procedure; T6, end of procedure; T7, 3 min after procedure; T8, 6 min after procedure; T9, 9 min after procedure