Table 1.
Characteristics of platelet rich-plasma.
| Parameter | Values |
|---|---|
| PRP preparation | |
| Initial blood volume | 32 ml (intraarticular) or 80 ml (intraosseous) |
| Anticoagulant | Sodium citrate 3.8% (w/v) |
| System | Close |
| Centrifugation | Yes |
| Number | 1 |
| Speed | 580 × g for 8 min |
| Final PRP volume | 8 ml (intraarticular) or 20 ml (intraosseous) |
| PRP characteristics | |
| PRP type | 13-00-11 |
| MPV | 9.60 fl (CI: 9.50–9.80) |
| Red blood cells | <0.01 × 106/µl |
| White blood cells | <0.05 × 106/µl |
| Neutrophils | – |
| Lymphocytes | – |
| Monocytes | – |
| Eosinophils | – |
| Basophils | – |
| Activation | CaCl2 (10% w/v) |
| Application characteristics | |
| Formulation type | Liquid |
| Administration route | Intraarticular or intraosseous |
| Dosage | 3 infiltrations on a weekly basis |
| Volume | Intraarticular injection: 8 ml Intraosseous injection: 3–5 ml |
| Dose (range of platelets) | Intraarticular injection:
2.37 × 109–2.62 × 109
Intraosseous injection: 0.89 × 109–1.64 × 109 |
| Tissue | Cartilage, synovium, subchondral bone |
| Pathology | Knee joint degeneration |
CI, confidence interval; PRP, platelet-rich plasma; MPV, mean platelet volume.