Table 3.
Univariate and Multivariate Logistic Regression Analysis to Identify Factors That Independently Predict Composite Adverse Events.
| Univariate | Multivariate | ||||
|---|---|---|---|---|---|
| Factors | n (%) | OR (95%CI) | P | Adjusted OR (95%CI) | P |
| Age |
|||||
| <65 years | 76/124 (61.3%) | * | |||
| ≥ 65 years | 9/20 (45.0%) | 0.517 (0.199-1.339) | .174 | 0.776 (0.270-2.229) | .637 |
| Vascular morbidity | |||||
| No | 55/91 (60.4%) | * | |||
| Yes | 30/53 (56.6%) | 0.854 (0.430-1.697) | .652 | ||
| ECOG | |||||
| 0 | 63/104 (60.6%) | * | |||
| 1 | 22/40 (55.0%) | 0.795 (0.381-1.662) | .543 | ||
| Stage | |||||
| I | 55/92 (59.8%) | * | |||
| II–III | 30/52 (57.7%) | 0.917 (0.460-1.829) | .806 | ||
| Chemotherapy | |||||
| Anthracycline | 79/132 (59.8%) | * | |||
| Non-anthracycline | 6/12 (50.0%) | 0.671 (0.205-2.192) | 0.509 | 0.820 (0.220-3.065) | .768 |
| WBC | |||||
| >5000 cell/mm3 | 73/128 (57.0%) | * | |||
| ≤5000 cell/mm3 | 12/16 (75.0%) | 2.260 (0.691-7.389) | .177 | 3.261 (0.921-11.545) | .067 |
| FFMI | |||||
| ≥14.85 kg/m2 | 23/59 (39.0%) | * | |||
| <14.85 kg/m2 | 62/85 (72.9%) | 4.219 (2.076-8.574) | <.001 | 4.562 (2.162-9.627) | <.001 |
| BMI | |||||
| ≥25 kg/m2 | 27/62 (43.5%) | * | |||
| <25 kg/m2 | 58/82 (70.7%) | 3.133 (1.569-6.256) | .001 | ** | |
Abbreviations: OR, odds ratio; CI, confidence interval; ECOG, Eastern Cooperative Oncology Group; WBC, white blood cell; FFMI, fat-free mass index; BMI, body mass index.
A P-value <.05 indicates statistical significance.
*Defined as reference.
**BMI was excluded from the multivariate analysis due to suspicion of multicollinearity.