Figure 3.

Scheme of the three interventional strata. (A) Stratum I: Patients with no measurable residual disease (R0-1-2). (B) Stratum II: Patients with measurable inoperable residual disease (R3–R4), WHO Grade II–III ependymoma, no metastasis. (C) Children <12 months or those not eligible to receive radiotherapy. *Multiple surgeries (more than 2) or poor neurological status; **Dose adaptation for children less than 10 kg. ^*multiple surgeries (more than 2) or poor neurological status; ^**dose adaptation for children less than 10 kg.