Table 3a.
Outcome measure values at each time point in Part A of the study (mean ± SD and range).
| Outcome measures | Day 0 | Day 14 | Day 28 | Overall time effect (p-value) |
|---|---|---|---|---|
| LOAD (0 to 52) | 23.8 ± 5.1 (17 to 33) | 19.2 ± 3.8 (14 to 36) | 19.5 ± 5.9 (10 to 34) | 0.057 |
| PVF (%BW) | 75.8 ± 18.9 (49.5 to 104.8) | 75.0 ± 18.0 (50.8 to 103.6) | 75.7 ± 18.8 (52.4 to 109.2) | 0.99 |
| VI (%BW·S) | 12.3 ± 3.5 (6.8 to 16.9) | 12.1 ± 3.3 (7.0 to 16.0) | 12.4 ± 3.6 (7.0 to 18.2) | 0.90 |
| SI for PVF | −19.5 ± 10.2 (−40.3 to −7.3) | −20.3 ± 10.0 (−38.1 to −5.0) | −16.8± 8.9 (−38.9 to −7.3) | 0.52 |
| SI for VI | −16.4 ± 9.8 (−35.7 to −5.2) | −15.9 ± 10.5 (−33.7 to −3.3) | −14.1 ± 7.1 (−32.2 to −6.2) | 0.55 |
| Accelerometry | 64.7 ± 35.3 (38.3 to 163.2) | 67.7 ± 32.0 (36.6 to 143.9) | 73.9 ± 46.1 (32.8 to 207.3) | 0.62 |
All kinetic variables (PVF and VI) normalized to percent body weight.
LOAD, Liverpool Osteoarthritis in Dogs; PVF, peak vertical force; VI, vertical impulse; SI, symmetry index.
Statistically significant: p < 0.05.