Table 2.
Causes of death for patients with stage I/II RCC.
| Timing of Death After Diagnosis | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| All Years | <1 year | 1 to <5 years | 5 to <10 years | ≥10 years | ||||||
| Cause of Death | No. (%) | SMR (95% CI) | No. (%) | SMR (95% CI) | No. (%) | SMR (95% CI) | No. (%) | SMR (95% CI) | No. (%) | SMR (95% CI) |
| All causes of death | 18,476 (100.00%) | 1.54# (1.52–1.56) | 2,069 (100.00%) | 1.81# (1.74–1.89) | 8,116 (100.00%) | 1.51# (1.48–1.54) | 6,459 (100.00%) | 1.52# (1.48–1.56) | 1,832 (100.00%) | 1.51# (1.44–1.58) |
| All malignant cancers | 7,126 (38.57%) | 2.45# (2.4–2.51) | 844 (40.79%) | 2.83# (2.64–3.03) | 3,416 (42.09%) | 2.53# (2.45–2.62) | 2,234 (34.59%) | 2.25# (2.16–2.34) | 632 (34.50%) | 2.39# (2.21–2.58) |
| Oral cavity/pharynx/eye/endocrine | 51 (0.28%) | 0.84 (0.62–1.1) | 5 (0.24%) | 0.81 (0.26–1.9) | 25 (0.31%) | 0.89 (0.57–1.31) | 15 (0.23%) | 0.72 (0.4–1.18) | 6 (0.33%) | 1.07 (0.39–2.32) |
| Digestive system | 815 (4.41%) | 1.08# (1.01–1.16) | 80 (3.87%) | 1.04 (0.83–1.3) | 327 (4.03%) | 0.93 (0.84–1.04) | 304 (4.71%) | 1.17# (1.04–1.31) | 104 (5.68%) | 1.50# (1.23–1.82) |
| Respiratory system | 803 (4.35%) | 0.97 (0.9–1.04) | 51 (2.46%) | 0.57# (0.42–0.74) | 361 (4.45%) | 0.92 (0.82–1.02) | 307 (4.75%) | 1.11 (0.99–1.24) | 84 (4.59%) | 1.2 (0.96–1.49) |
| Bones and joints/soft tissue/skin | 70 (0.38%) | 0.81 (0.63–1.02) | 9 (0.43%) | 1.04 (0.48–1.98) | 26 (0.32%) | 0.65# (0.43–0.96) | 25 (0.39%) | 0.83 (0.54–1.23) | 10 (0.55%) | 1.23 (0.59–2.26) |
| Breast | 51 (0.28%) | 0.38# (0.28–0.5) | 2 (0.10%) | 0.14# (0.02–0.51) | 13 (0.16%) | 0.21# (0.11–0.35) | 25 (0.39%) | 0.55# (0.36–0.82) | 11 (0.60%) | 0.93 (0.47–1.67) |
| Genital system | 183 (0.99%) | 0.61# (0.53–0.71) | 16 (0.77%) | 0.55# (0.32–0.9) | 81 (1.00%) | 0.60# (0.48–0.74) | 58 (0.90%) | 0.55# (0.42–0.71) | 28 (1.53%) | 0.94 (0.63–1.36) |
| Kidney and renal pelvis | 4,273 (23.13%) | 59.77# (57.99–61.59) | 584 (28.23%) | 79.88# (73.53–86.63) | 2,189 (26.97%) | 66.01# (63.27–68.83) | 1,200 (18.58%) | 49.00# (46.26–51.85) | 300 (16.38%) | 46.01# (40.95–51.52) |
| Other urinary organs | 98 (0.53%) | 1.04 (0.85–1.27) | 7 (0.34%) | 0.81 (0.33–1.67) | 56 (0.69%) | 1.34# (1.01–1.74) | 29 (0.45%) | 0.86 (0.57–1.23) | 6 (0.33%) | 0.61 (0.22–1.33) |
| Brain/other nervous system | 98 (0.53%) | 1.48# (1.2–1.81) | 7 (0.34%) | 1.03 (0.41–2.11) | 46 (0.57%) | 1.49# (1.09–1.99) | 36 (0.56%) | 1.61# (1.12–2.22) | 9 (0.49%) | 1.52 (0.7–2.89) |
| Lymph/blood | 315 (1.70%) | 1.1 (0.98–1.23) | 45 (2.17%) | 1.58# (1.15–2.11) | 129 (1.59%) | 0.99 (0.82–1.17) | 110 (1.70%) | 1.1 (0.91–1.33) | 31 (1.69%) | 1.14 (0.78–1.62) |
| Miscellaneous malignant cancer | 369 (2.00%) | 1.69# (1.52–1.87) | 38 (1.84%) | 1.71# (1.21–2.35) | 163 (2.01%) | 1.62# (1.38–1.89) | 125 (1.94%) | 1.66# (1.38–1.98) | 43 (2.35%) | 2.10# (1.52–2.83) |
| In situ, benign or unknown behavior neoplasm | 115 (0.62%) | 1.51# (1.25–1.81) | 14 (0.68%) | 1.98# (1.08–3.33) | 51 (0.63%) | 1.51# (1.12–1.98) | 43 (0.67%) | 1.57# (1.13–2.11) | 7 (0.38%) | 0.89 (0.36–1.83) |
| Noncancer | 11,235 (60.81%) | 1.25# (1.22–1.27) | 1,211 (58.53%) | 1.45# (1.37–1.53) | 4,649 (57.28%) | 1.16# (1.13–1.2) | 4,182 (64.75%) | 1.29# (1.25–1.33) | 1,193 (65.12%) | 1.27# (1.2–1.34) |
| Infections | 446 (2.41%) | 1.50# (1.36–1.64) | 59 (2.85%) | 1.96# (1.49–2.53) | 193 (2.38%) | 1.41# (1.22–1.62) | 155 (2.40%) | 1.51# (1.28–1.77) | 39 (2.13%) | 1.4 (1–1.91) |
| Diabetes mellitus | 721 (3.90%) | 1.91# (1.77–2.05) | 92 (4.45%) | 2.45# (1.98–3.01) | 309 (3.81%) | 1.78# (1.59–1.99) | 257 (3.98%) | 1.95# (1.72–2.21) | 63 (3.44%) | 1.74# (1.34–2.22) |
| Alzheimer’s (ICD-9 and 10 only) | 363 (1.96%) | 0.84# (0.75–0.93) | 20 (0.97%) | 0.64# (0.39–0.98) | 114 (1.40%) | 0.66# (0.54–0.79) | 170 (2.63%) | 1 (0.86–1.17) | 59 (3.22%) | 1.01 (0.77–1.3) |
| Diseases of heart | 3,718 (20.12%) | 1.23# (1.19–1.27) | 411 (19.86%) | 1.42# (1.29–1.56) | 1,567 (19.31%) | 1.16# (1.1–1.22) | 1,350 (20.90%) | 1.26# (1.19–1.33) | 390 (21.29%) | 1.26# (1.14–1.39) |
| Hypertension without heart disease | 320 (1.73%) | 2.25# (2.01–2.52) | 30 (1.45%) | 2.46# (1.66–3.51) | 121 (1.49%) | 1.97# (1.64–2.36) | 126 (1.95%) | 2.40# (2–2.86) | 43 (2.35%) | 2.70# (1.96–3.64) |
| Cerebrovascular diseases | 710 (3.84%) | 1.11# (1.03–1.19) | 75 (3.62%) | 1.26 (0.99–1.58) | 317 (3.91%) | 1.12# (1–1.25) | 237 (3.67%) | 1.03 (0.9–1.17) | 81 (4.42%) | 1.18 (0.94–1.47) |
| Diseases of arteries | 154 (0.83%) | 1.21# (1.02–1.41) | 25 (1.21%) | 1.91# (1.23–2.82) | 57 (0.70%) | 0.97 (0.74–1.26) | 59 (0.91%) | 1.35# (1.03–1.74) | 13 (0.71%) | 1.08 (0.57–1.84) |
| Pneumonia and influenza | 1,022 (5.53%) | 1.01 (0.95–1.08) | 94 (4.54%) | 1 (0.81–1.22) | 414 (5.10%) | 0.92 (0.83–1.01) | 419 (6.49%) | 1.16# (1.05–1.28) | 95 (5.19%) | 0.92 (0.74–1.12) |
| Digestive | 231 (1.25%) | 1.41# (1.23–1.6) | 31 (1.50%) | 1.78# (1.21–2.53) | 110 (1.36%) | 1.42# (1.16–1.71) | 76 (1.18%) | 1.39# (1.1–1.74) | 14 (0.76%) | 1 (0.55–1.68) |
| Nephritis/nephrotic syndrome/nephrosis | 716 (3.88%) | 2.95# (2.74–3.18) | 78 (3.77%) | 3.43# (2.71–4.29) | 287 (3.54%) | 2.65# (2.35–2.97) | 266 (4.12%) | 3.07# (2.71–3.46) | 85 (4.64%) | 3.42# (2.73–4.23) |
| Pregnancy/childbirth/puerperium | 28 (0.15%) | 2.27# (1.51–3.28) | 1 (0.05%) | 0.74 (0.02–4.15) | 11 (0.14%) | 1.87 (0.93–3.34) | 12 (0.19%) | 2.94# (1.52–5.14) | 4 (0.22%) | 3.83# (1.04–9.8) |
| Symptoms, signs, and ill-defined conditions | 150 (0.81%) | 1.16 (0.98–1.36) | 15 (0.72%) | 1.23 (0.69–2.04) | 65 (0.80%) | 1.12 (0.86–1.43) | 60 (0.93%) | 1.29 (0.98–1.65) | 10 (0.55%) | 0.82 (0.39–1.5) |
| Accidents/adverse effects/homicide/legal intervention | 468 (2.53%) | 1.13# (1.03–1.24) | 50 (2.42%) | 1.21 (0.9–1.59) | 210 (2.59%) | 1.1 (0.96–1.26) | 159 (2.46%) | 1.11 (0.95–1.3) | 49 (2.67%) | 1.24 (0.91–1.63) |
| Suicide/self-inflicted injury | 105 (0.57%) | 1.01 (0.82–1.22) | 8 (0.39%) | 0.68 (0.3–1.35) | 50 (0.62%) | 0.99 (0.73–1.3) | 38 (0.59%) | 1.12 (0.8–1.54) | 9 (0.49%) | 1.08 (0.5–2.06) |
| Other cause of death | 2,083 (11.27%) | 1.10# (1.06–1.15) | 222 (10.73%) | 1.38# (1.2–1.57) | 824 (10.15%) | 1.01 (0.95–1.09) | 798 (12.35%) | 1.14# (1.06–1.22) | 239 (13.05%) | 1.14 (1–1.29) |
#p < 0.05; SMRs, standardized mortality ratios; CI, confidence interval.