Table 3.
Causes of death for patients with stage III RCC.
| Timing of Death After Diagnosis | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| All Years | <1 year | 1 to <5 years | 5 to <10 years | ≥10 years | ||||||
| Cause of Death | No. (%) | SMR (95% CI) | No. (%) | SMR (95% CI) | No. (%) | SMR (95% CI) | No. (%) | SMR (95% CI) | No. (%) | SMR (95% CI) |
| All causes of death | 6,612 (100.00%) | 2.93# (2.86–3) | 1,174 (100.00%) | 4.54# (4.29–4.81) | 3,400 (100.00%) | 3.15# (3.05–3.26) | 1,672 (100.00%) | 2.30# (2.19–2.41) | 366 (100.00%) | 1.88# (1.69–2.08) |
| All malignant cancers | 4,574 (69.18%) | 8.31# (8.07–8.55) | 888 (75.64%) | 13.07# (12.23–13.96) | 2,530 (74.41%) | 9.33# (8.97–9.7) | 968 (57.89%) | 5.70# (5.35–6.07) | 188 (51.37%) | 4.52# (3.89–5.21) |
| Oral cavity/pharynx/eye/endocrine | 8 (0.12%) | 0.69 (0.3–1.36) | 2 (0.17%) | 1.42 (0.17–5.13) | 0 (0.00%) | 0.00# (0–0.65) | 4 (0.24%) | 1.12 (0.3–2.86) | 2 (0.55%) | 2.25 (0.27–8.13) |
| Digestive system | 142 (2.15%) | 1 (0.84–1.18) | 18 (1.53%) | 1.03 (0.61–1.63) | 69 (2.03%) | 0.98 (0.77–1.25) | 46 (2.75%) | 1.05 (0.77–1.39) | 9 (2.46%) | 0.83 (0.38–1.58) |
| Respiratory system | 176 (2.66%) | 1.1 (0.94–1.28) | 11 (0.94%) | 0.53# (0.26–0.94) | 88 (2.59%) | 1.1 (0.88–1.35) | 60 (3.59%) | 1.26 (0.96–1.62) | 17 (4.64%) | 1.54 (0.9–2.47) |
| Bones and joints/soft tissue/skin | 17 (0.26%) | 0.99 (0.57–1.58) | 3 (0.26%) | 1.46 (0.3–4.26) | 9 (0.26%) | 1.07 (0.49–2.03) | 4 (0.24%) | 0.74 (0.2–1.89) | 1 (0.27%) | 0.74 (0.02–4.1) |
| Breast | 13 (0.20%) | 0.65 (0.35–1.12) | 1 (0.09%) | 0.39 (0.01–2.2) | 2 (0.06%) | 0.20# (0.02–0.74) | 7 (0.42%) | 1.16 (0.47–2.4) | 3 (0.82%) | 2.02 (0.42–5.91) |
| Genital system | 26 (0.39%) | 0.47# (0.3–0.68) | 1 (0.09%) | 0.15# (0–0.86) | 10 (0.29%) | 0.37# (0.18–0.69) | 14 (0.84%) | 0.78 (0.43–1.32) | 1 (0.27%) | 0.21 (0.01–1.2) |
| Kidney and renal pelvis | 3,912 (59.17%) | 279.28# (270.6–288.17) | 806 (68.65%) | 468.31# (436.54–501.79) | 2,211 (65.03%) | 320.15# (306.94–333.78) | 758 (45.33%) | 175.32# (163.06–188.26) | 137 (37.43%) | 129.65# (108.85–153.27) |
| Other urinary organs | 44 (0.67%) | 2.28# (1.65–3.05) | 2 (0.17%) | 0.93 (0.11–3.37) | 28 (0.82%) | 3.06# (2.03–4.42) | 13 (0.78%) | 2.05# (1.09–3.5) | 1 (0.27%) | 0.59 (0.01–3.27) |
| Brain/other nervous system | 22 (0.33%) | 1.76# (1.1–2.66) | 0 (0.00%) | 0 (0–2.37) | 14 (0.41%) | 2.24# (1.23–3.76) | 7 (0.42%) | 1.83 (0.74–3.78) | 1 (0.27%) | 1.09 (0.03–6.08) |
| Lymph/blood | 52 (0.79%) | 0.93 (0.69–1.22) | 8 (0.68%) | 1.2 (0.52–2.36) | 27 (0.79%) | 0.99 (0.66–1.45) | 13 (0.78%) | 0.74 (0.39–1.26) | 4 (1.09%) | 0.9 (0.24–2.3) |
| Miscellaneous malignant cancer | 162 (2.45%) | 3.86# (3.29–4.51) | 36 (3.07%) | 7.05# (4.94–9.76) | 72 (2.12%) | 3.51# (2.75–4.42) | 42 (2.51%) | 3.22# (2.32–4.36) | 12 (3.28%) | 3.66# (1.89–6.4) |
| In situ, benign or unknown behavior neoplasm | 24 (0.36%) | 1.60# (1.03–2.38) | 3 (0.26%) | 1.8 (0.37–5.26) | 9 (0.26%) | 1.27 (0.58–2.41) | 9 (0.54%) | 1.83 (0.84–3.48) | 3 (0.82%) | 2.28 (0.47–6.66) |
| Noncancer | 2,014 (30.46%) | 1.19# (1.14–1.24) | 283 (24.11%) | 1.50# (1.33–1.68) | 861 (25.32%) | 1.08# (1.01–1.15) | 695 (41.57%) | 1.26# (1.17–1.35) | 175 (47.81%) | 1.15 (0.99–1.33) |
| Infections | 95 (1.44%) | 1.78# (1.44–2.17) | 25 (2.13%) | 3.89# (2.52–5.74) | 32 (0.94%) | 1.23 (0.84–1.73) | 28 (1.67%) | 1.67# (1.11–2.41) | 10 (2.73%) | 2.34# (1.12–4.31) |
| Diabetes mellitus | 130 (1.97%) | 1.87# (1.57–2.22) | 13 (1.11%) | 1.57 (0.84–2.69) | 61 (1.79%) | 1.81# (1.38–2.32) | 43 (2.57%) | 1.97# (1.42–2.65) | 13 (3.55%) | 2.33# (1.24–3.99) |
| Alzheimer’s (ICD-9 and 10 only) | 61 (0.92%) | 0.75# (0.58–0.97) | 3 (0.26%) | 0.42 (0.09–1.23) | 26 (0.76%) | 0.74 (0.49–1.09) | 25 (1.50%) | 0.86 (0.56–1.27) | 7 (1.91%) | 0.72 (0.29–1.48) |
| Diseases of heart | 708 (10.71%) | 1.23# (1.14–1.32) | 109 (9.28%) | 1.64# (1.35–1.98) | 298 (8.76%) | 1.09 (0.97–1.22) | 249 (14.89%) | 1.34# (1.18–1.52) | 52 (14.21%) | 1.03 (0.77–1.35) |
| Hypertension without heart disease | 41 (0.62%) | 1.63# (1.17–2.2) | 4 (0.34%) | 1.54 (0.42–3.93) | 13 (0.38%) | 1.12 (0.6–1.92) | 20 (1.20%) | 2.34# (1.43–3.61) | 4 (1.09%) | 1.63 (0.44–4.16) |
| Cerebrovascular diseases | 146 (2.21%) | 1.23# (1.04–1.44) | 20 (1.70%) | 1.5 (0.92–2.32) | 65 (1.91%) | 1.16 (0.9–1.48) | 50 (2.99%) | 1.29 (0.95–1.69) | 11 (3.01%) | 1 (0.5–1.79) |
| Diseases of arteries | 22 (0.33%) | 0.89 (0.56–1.35) | 1 (0.09%) | 0.33 (0.01–1.83) | 12 (0.35%) | 1 (0.52–1.75) | 7 (0.42%) | 0.92 (0.37–1.9) | 2 (0.55%) | 1.02 (0.12–3.69) |
| Pneumonia and influenza | 191 (2.89%) | 0.97 (0.84–1.12) | 19 (1.62%) | 0.86 (0.52–1.34) | 81 (2.38%) | 0.87 (0.69–1.08) | 73 (4.37%) | 1.15 (0.9–1.44) | 18 (4.92%) | 1.06 (0.63–1.67) |
| Digestive | 48 (0.73%) | 1.60# (1.18–2.13) | 5 (0.43%) | 1.3 (0.42–3.04) | 21 (0.62%) | 1.39 (0.86–2.12) | 17 (1.02%) | 1.92# (1.12–3.07) | 5 (1.37%) | 2.43 (0.79–5.67) |
| Nephritis/nephrotic syndrome/nephrosis | 94 (1.42%) | 2.10# (1.69–2.57) | 6 (0.51%) | 1.19 (0.44–2.6) | 43 (1.26%) | 2.02# (1.46–2.72) | 33 (1.97%) | 2.26# (1.55–3.17) | 12 (3.28%) | 3.07# (1.59–5.36) |
| Pregnancy/childbirth/puerperium | 6 (0.09%) | 2.84# (1.04–6.17) | 2 (0.17%) | 7.26 (0.88–26.23) | 3 (0.09%) | 2.8 (0.58–8.19) | 1 (0.06%) | 1.61 (0.04–8.95) | 0 (0.00%) | 0 (0–25.11) |
| Symptoms, signs, and ill-defined conditions | 35 (0.53%) | 1.47# (1.03–2.05) | 8 (0.68%) | 3.01# (1.3–5.92) | 19 (0.56%) | 1.68# (1.01–2.63) | 8 (0.48%) | 1.02 (0.44–2.01) | 0 (0.00%) | 0 (0–1.87) |
| Accidents/adverse effects/homicide/legal intervention | 64 (0.97%) | 0.86 (0.66–1.1) | 8 (0.68%) | 0.91 (0.39–1.8) | 34 (1.00%) | 0.94 (0.65–1.32) | 20 (1.20%) | 0.86 (0.53–1.33) | 2 (0.55%) | 0.33 (0.04–1.18) |
| Suicide/self-inflicted injury | 13 (0.20%) | 0.67 (0.36–1.15) | 1 (0.09%) | 0.39 (0.01–2.17) | 10 (0.29%) | 1.01 (0.48–1.86) | 2 (0.12%) | 0.36 (0.04–1.29) | 0 (0.00%) | 0 (0–2.93) |
| Other cause of death | 360 (5.44%) | 1.02 (0.91–1.13) | 59 (5.03%) | 1.62# (1.23–2.09) | 143 (4.21%) | 0.88 (0.74–1.03) | 119 (7.12%) | 0.99 (0.82–1.18) | 39 (10.66%) | 1.14 (0.81–1.56) |
#p < 0.05; SMRs, standardized mortality ratios; CI, confidence interval.