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. 2022 Jun 2;9:843096. doi: 10.3389/fnut.2022.843096

Figure 3.

Figure 3

Effects of LEO and DEO on plasma concentration of tumor necrosis factor α [TNF-α; (A)], interleukin-1β [IL-1β; (B)], and interleukin 6 [IL-6; (C)] in E. coli injected mice. Data were presented as mean ± standard error of mean (mean ± SEM) (n = 8). The 1st column was normal saline group (NS) with no E. coli and no EO. The 2nd column was the E. coli group with no EO. The 3rd−8th column are the LEO and DEO groups with doses at 300, 600, and 1,200 mg/kg BW, respectively. #P < 0.05 and ##P < 0.01, E. coli group compared with NS group; Essential oil (E) and its different dose (D) had significant effects on plasma inflammatory factors (PE < 0.01, PD < 0.01), and their interaction (E × D) was significant (PE × PD < 0.01). **P < 0.01, EO groups compared with E. coli group. LEO, lemon essential oil; DEO, d-limonene essential oil.