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. 2021 Nov 20;17(2):1024–1029. doi: 10.1016/j.jds.2021.10.019

Table 1.

Patient characteristics

Factor Number of patients / Mean ± standard deviation
p value
Total Oral cancer Oropharyngeal cancer
Age (years) 65.8 ± 11.6 66.0 ± 12.5 65.3 ± 9.67 0.582
Sex Female 94 80 14 <0.001
Male 272 162 110
Diabetes (−) 301 195 106 0.312
(+) 65 47 18
Leukocytes 2969 ± 1234 3056 ± 1295 2800 ± 1092 0.060
Lymphocytes 441 ± 310 488 ± 325 351 ± 258 <0.001
Creatinine 0.877 ± 0.736 0.803 ± 0.678 1.02 ± 0.822 0.007
Albumin 3.64 ± 0.537 3.67 ± 0.516 3.57 ± 0.571 0.086
Total dose 64.3 ± 5.13 62.7 ± 4.95 67.6 ± 3.79 <0.001
Neck dissection before RT (−) 138 45 93 <0.001
(+) 228 197 31
RT method 3D-CRT 277 211 66 <0.001
IMRT 89 31 58
Concurrent therapy RT alone 115 98 17 <0.001
CRT 214 133 81
BRT 37 11 26
Remaining teeth (−) 26 19 7 0.523
(+) 340 223 117
Alveolar bone loss 50% or less 231 163 68 0.022
more than 50% 135 79 56
Periapical lesion at the start of RT (−) 310 206 104 0.761
(+) 56 36 20
Severe periodontal disease at the start of RT (−) 334 218 116 0.330
(+) 32 24 8
Tooth extraction before RT (−) 215 151 64 0.056
(+) 151 91 60
Tooth extraction after RT (−) 332 221 111 0.573
(+) 34 21 13
Total 366 242 124

Abbreviations: 3D-CRT: three dimensional conformal radiotherapy; BRT: bio-radiotherapy; CRT: chemo-radiotherapy; IMRT: intensity modulated radiotherapy; RT: radiotherapy.