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. 2022 Jun 2;13:850405. doi: 10.3389/fneur.2022.850405

Table 3.

Unadjusted and adjusted associations between liver fibrosis indices and outcomes.

Multivariable adjustment OR (95%CI)
Outcome Event, n (%) FIB−4 cutoff 3.25 APRI cutoff 0.7 Forns cutoff 6.9
Mortality at 90 days 411/3722(11%) 1.35(1.02–1.77) 1.39(1.08–1.78) 1.53(1.11–2.12)
Mortality at 180 days 466/3722(12.5) 1.37(1.05–1.78) 1.44(1.13–1.82) 1.57(1.15–2.13)
Mortality at one year 527/3722(14.2) 1.38(1.07–1.77) 1.42(1.13–1.78) 1.58(1.18–2.13)
Mortality at three years 527/3722(14.2) 1.40(1.09–1.79) 1.34(1.07–1.69) 1.65(1.23–2.21)
Acute kidney injury 176/3722(4.7%) 1.43(0.99–2.08) 1.16(0.82–1.66) 1.27(0.82–1.97)
Pneumonia 976/3722(26.2) 1.05(0.85–1.29) 1.02(0.85–1.23) 1.27(1.00–1.63)
Hydrocephalus 391/3722(10.5) 1.00(0.75–1.32) 0.99(0.76–1.29) 1.34(0.96–1.86)
Rebleeding 183/3722(4.9%) 1.64(1.14–2.36) 1.69(1.22–2.34) 1.54(1.01–2.36)
Delayed cerebral ischemia 698/3722(18.8) 1.00(0.81–1.24) 1.19(0.98–1.44) 1.14(0.88–1.49)

APRI, Aspartate Aminotransferase/Platelet Ratio Index; FIB−4, Fibrosis−4.