Table 5.

Regression analysis of spatial navigation performance and CSF biomarkers controlled for demographic characteristics.

CSF biomarkers	Spatial navigation performance (% correct)
	Standardized Regression Coefficient β	Unstandardized Regression Coefficient B	Standard Error of Measurement SE	R Square
	Route-repetition task
Amyloid-β1–42 (pg/ml)	0.394**	0.024**	0.008	0.289
	Route-retracing task
P-tau181 (pg/ml)	-0.283*	-0.100*	0.048	0.265
	Directional-approach task
Amyloid-β1–42 (pg/ml)	0.241	0.016	0.009	0.243
Total tau (pg/ml)	-0.215	-0.011	0.007	0.232
P-tau181 (pg/ml)	-0.298*	-0.098*	0.045	0.270

*p < 0.05; **p < 0.01. Key: CSF, cerebrospinal fluid; p-tau₁₈₁, phosphorylated tau₁₈₁.