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. 2022 Jun 2;16:913052. doi: 10.3389/fnbot.2022.913052

Table 2.

Methodological quality assessment by the modified QualSyst quality appraisal tool.

Q1 Q2 Q3 Q4 Q5 Q6 Q7 Q8 Q9 Q10 Total Summary score
Stetter et al. (2020) +2 +1 +1 +1 +2 +1 +2 +2 +2 +2 16 0.80
Stetter et al. (2019) +2 +1 +2 +1 +2 +1 +2 +2 +2 +2 17 0.85
Hernandez et al. (2021) +2 +1 +2 +2 +2 +2 +2 +2 +2 +2 19 0.95
Gholami et al. (2020) +2 +2 +2 +1 +2 +1 N/A +1 +2 +2 15 0.83
Wouda et al. (2018) +2 +2 +2 +2 +2 +1 +2 +2 +2 +2 19 0.95
Derie et al. (2020) +2 +1 +2 +2 +2 +2 +2 +2 +2 +2 19 0.95
Liu et al. (2020) +2 +1 +2 +2 +2 +1 +2 +2 +1 +2 17 0.85
Rapp et al. (2021) +2 +2 +2 +1 +2 +2 +2 +2 +2 +2 19 0.95
Ngoh et al. (2018) +2 +2 +2 +1 +2 +1 N/A +2 +2 +2 16 0.89
Young et al. (2020) 2 2 1 1 2 2 N/A 1 1 2 14 0.78
Robberechts et al. (2021) +2 +2 +2 +2 +2 +2 +2 +2 +2 +2 20 1.00
Zrenner et al. (2018) +2 +2 +2 +1 +2 +2 N/A +2 +2 +2 17 0.94
Komaris et al. (2019) +1 +1 +2 +2 +2 +2 +2 +2 +2 +2 18 0.90
Tan et al. (2019) +2 +1 +2 +1 +2 +1 N/A +1 +2 +2 14 0.78
Watari et al. (2018a) +2 +2 +2 +2 +2 +1 +2 +2 +1 +2 18 0.90
Watari et al. (2018b) +2 +2 +2 +2 +2 +1 +2 +2 +2 +2 19 0.95
Ahamed et al. (2019) +2 +2 +2 +1 +2 +1 +2 +2 +2 +2 18 0.90
Ahamed et al. (2018) +2 +2 +2 +2 +2 +1 +2 +2 +2 +2 19 0.95
Clermont et al. (2019a) +2 +2 +2 +2 +2 +1 +2 +2 +2 +2 19 0.95
Dixon et al. (2019) +2 +2 +2 +2 +2 +2 N/A +2 +2 +2 18 1.00
Johnson et al. (2021) +2 +2 +2 +1 +2 +2 N/A +2 +2 +2 17 0.94
Tan et al. (2020) +2 +2 +2 +1 +2 +1 +2 +2 +2 +2 18 0.90
Koska and Maiwald (2020) +2 +2 +2 +2 +2 +1 N/A +2 +2 +2 17 0.94
Matijevich et al. (2020) +2 +2 +2 +1 +2 +1 +2 +2 +2 +2 18 0.90
0.91

2 = “yes”, 1 = “partial”, 0 = “no”. N/A means that study should not be checked for this question. Summary score = total sum/total possible sum.

Q1: Question or objective clearly described?

Q2: Design evident and appropriate to answer the study question?

Q3: Method of subject selection or source of information/input variables is described and appropriate.

Q4: Subject characteristics or input variables/information sufficiently described?

Q5: Outcome well defined and robust to measurement/misclassification bias? Means of assessment reported?

Q6: Sample size appropriate?

Q7: Analysis described and appropriate?

Q8: Some estimate of variance is reported for the main results?

Q9: Results reported in sufficient detail?

Q10: Do the results support the conclusions?