TABLE 4.

Functional enrichment analysis of hub genes.

Term	Description	Count in gene set	-LogP	Gene symbol
GO:0006954	inflammatory response	7	10.91830694	CD44,HIF1A,IL1B,CXCL8,SPP1,TIMP1,CXCR4
GO:0034097	response to cytokine	7	9.518326992	CD44,HIF1A,ICAM1,IL1B,CXCL8,TIMP1,CXCR4
GO:2001234	negative regulation of apoptotic signaling pathway	5	8.550111382	CD44,HIF1A,ICAM1,IL1B,MMP9,
GO:0050900	positive regulation of angiogenesis	5	8.502623951	ICAM1,IL1B,CXCL8,MMP9,CXCR4
GO:0030335	positive regulation of cell migration	6	8.499677873	HIF1A,ICAM1,IL1B,CXCL8,MMP9,CXCR4
GO:0007159	leukocyte cell-cell adhesion	3	6.322506413	CD44,ICAM1,IL1B
GO:0050767	regulation of neurogenesis	4	5.618029472	HIF1A,IL1B,SPP1,CXCR4
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	3	5.50966188	CD44,HIF1A,MMP9
hsa04670	Leukocyte transendothelial migration	3	5.364159855	ICAM1,MMP9,CXCR4
GO:0002009	morphogenesis of an epithelium	3	3.60847974	CD44,HIF1A,CXCR4