Table 2.

Summary of observed pathways/reactions were affected as a consequence of the different gases and concentrations for both species of photobacteria.

	P. carnosum	P. phosphoreum
Oxygen (21%)	Respiratory chain Oxidoreductase activity Pyruvate metabolism *(TMW 2.2021T) TCA cycle Synthesis lipoic acid Oxygen consuming reactions Synthesis of valine, leucine, isoleucine Oxidative stress *(TMW 2.2021T) Degradation of fatty acids *(TMW 2.2149)	Oxidoreductase activity Degradation of fatty acids
Oxygen (70%)	Oxidative stress Iron uptake	Oxidative stress Heme utilization/transport Iron-sulfur cluster assembly Histidine biosynthesis *(TMW 2.2103)
Vacuum (N2)	Respiratory chain *(TMW 2.2021T) Alternative electron acceptors/donors Carbohydrate utilization Peptidases/proteases pH homeostasis Osmoregulation *(TMW 2.2021T)	Respiratory chain Alternative electron acceptors/donors Carbohydrate utilization Peptidases/proteases pH homeostasis Osmoregulation
Carbon dioxide	pH homeostasis *(TMW 2.2149) Cellular stress *(TMW 2.2021T)	Redox sensing *(TMW 2.2103) Protein S-thiolation *(TMW 2.2134)
Carbon dioxide + Oxygen (21%)	Oxidative stress *(TMW 2.2149) Cellular stress *(TMW 2.2149) pH homeostasis	Oxidative stress Cellular stress pH homeostasis
Carbon dioxide + Oxygen (70%)		Respiratory chain Oxidoreductase activity Alternative electron acceptors/donors Pyruvate metabolism TCA cycle Glyoxylate cycle Fatty acid degradation Amino acids metabolism Heme utilization/transport Iron-sulfur cluster assembly

Strain-specific regulations are marked with an asterisk and the strain that showed the regulation specified between brackets. Pathway assignation was performed manually.