TABLE 2.

Univariable and multivariable generalized linear mixed model analysis for unbalanced translocation.

	Univariate generalized linear mixed model (GLMM)		Multivariable generalized linear mixed model (GLMM)
	OR (95% CI)	p	OR (95% CI)	p
Size 1	0.999 (0.998,1.000)	0.006
TAR1	0.823 (0.711,0.954)	0.01	0.806 (0.696,0.933)	0.004
CS2	0.999 (0.998,1.000)	0.029
Sex
Female	1.295 (1.189,1.411)	<0.001	1.293 (1.187,1.408)	<0.001
Male	Reference		Reference
Acr-ch
With	1.22 (1.115, 1.333)	<0.001	1.208 (1.089,1.339)	<0.001
Without	Reference		Reference

Acr-ch, acrocentric chromosome;

Size 1, size of the longer chromosome involved;

CS 2, size of the centric segments of the shorter chromosome involved;

TAR1, the ratio of the translocated segment over the chromosome arm of the longer chromosome.