TABLE 1.

Protocol data used for molecular docking validation.

Receptor	Ligand/ID	Coordinates of grid center	Grid box size
Chk1 (Homo sapiens) PDB ID: 2CGX	2-[(6-amino-7h-purin-8-yl)thio]acetamide/3D3	X = 4.602	20x
		Y = -5.735	28y
		Z = 17.765	18z
elF4A1-ATP (Homo sapiens) (PDB ID: 5ZC9)	(1R,2R,3S,3aR,8bS)-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-1,8b-bis(oxidanyl)-3-phenyl-2,3-dihydro-1H-cyclopenta [b][1]benzofuran-2-carboxamide/RCG	X = 42.459	32x
		Y = 5.194	38y
		Z = 44.166	32z
BRAF kinase (Homo sapiens) (PDB ID: 6XFP)	4-amino-N-{1-[(3-chloro-2-fluorophenyl)amino]-6-methylisoquinolin-5-yl}thieno [3,2-days]pyrimidine-7-carboxamide/V1Y	X = -3.752	38x
		Y = 15.954	38y
		Z = 13.702	24z