Biocatalytic synthesis of benzamide from benzonitrile in biphasic reaction systems.
| ||||
|---|---|---|---|---|
| Solvent | Conversiona [%] | Distribution of amide [%] | ||
| Organic phase | Aqueous phase | |||
| 1 | n-Hexane | >99 | n.d.b | >99 |
| 2 | Amyl acetate | >99 | >99 | n.d. |
| 3 | Toluene | >99 | 23.3 | 76.7 |
| 4 | Nonec | >99 | n.d.d | >99 |
a
The conversion of BN to BAM was determined by HPLC analysis.
b
No product was detected.
c
The control group was carried out in PPB (pH 7.0).
d
The catalysis was performed in a pure aqueous solution, so the analysis was not conducted.