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. 2022 Jun 2;13:844073. doi: 10.3389/fendo.2022.844073

Table 2.

Association of the TyG index with leukocyte telomere length.

TyG index LTL, bp
Model 1 Model 2 Model 3
β (95% CI) P value β (95% CI) P value β (95% CI) P value
Continuous -61.95 (-88.23, -35.66) <0.001 -58.87 (-86.28, -31.47) <0.001 -72.62 (-107.36, -37.87) <0.001
Tertiles
T1 (<8.27) 0 (Reference) 0 (Reference) 0 (Reference)
T2 (8.27-8.77) -27.07 (-65.46, 11.32) 0.167 -7.75 (-46.27, 30.78) 0.694 -4.31 (-48.12, 39.49) 0.847
T3 (≥ 8.77) -87.77 (-126.34, -49.21) <0.001 -78.50 (-118.25, -38.75) 0.003 -95.98 (-145.08, -46.89) <0.001
Categories
T1-T2 (<8.77) 0 (Reference) 0 (Reference) 0 (Reference)
T3 (≥ 8.77) -73.86 (-107.00, -40.72) <0.001 -74.24 (-107.87, -40.61) <0.001 -93.33 (-134.33, -52.32) <0.001

TyG, triglyceride glucose; LTL, leukocyte telomere length; CI, confidence interval. Model 1 was adjusted for age. Model 2 was adjusted for age, sex, education, smoking status, alcohol consumption, physical activity, and BMI. Model 3 was adjusted for age, sex, education, smoking status, alcohol consumption, physical activity, BMI, waist circumference, SBP, DBP, history of hypertension, TC, SUA, eGFR, and CRP.