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. 2022 Jun 3;7(23):20298–20305. doi: 10.1021/acsomega.2c02298

Figure 7.

Figure 7

DNA sensing using MB as a DNA intercalator and a three-electrode system. (A) Changes in cyclic voltammograms in 50 mM PBS (pH 7.4) containing 100 mM KNO3 after sequential modification with pDNA and MCH on a bare gold electrode. (B) Cyclic voltammograms obtained with 20, 100, 500, and 1000 μM MB and a bare gold electrode as the working electrode. (C) Cyclic voltammograms after incubating 1, 5, or 10 μM tDNA and 100 μM MB on the gold electrode with immobilized pDNA and MCH. (D) Dependence of the reduction peak current in panel C on tDNA concentration (CtDNA) (n = 3). The red circles and error bars indicate the averages and standard deviations. All cyclic voltammograms were obtained at a scan rate of 50 mV/s.