Table 3.
Differential metabolites and their metabolic pathways between the Model and HA + GA group
| MS2kegg | RT | M/Z | Formula | Regulated | Identification | Pathway |
|---|---|---|---|---|---|---|
| C07446 | 1.07 | 124.0387 | C6H5NO2 | up | Isonicotinic acid | Drug metabolism - other enzymes |
| C00319 | 3.20 | 300.2893 | C18H37NO2 | down | sphingosine | Sphingolipid metabolism |
| C00319 | 3.20 | 300.2893 | C18H37NO2 | down | sphingosine | Metabolic pathways |
| C00319 | 3.20 | 300.2893 | C18H37NO2 | down | sphingosine | Sphingolipid signaling pathway |
| C00319 | 3.20 | 300.2893 | C18H37NO2 | down | sphingosine | Apoptosis |
| C00157 | 4.96 | 580.3945 | C10H18N08PR2 | up | Phosphatidylcholine | Glycerophospholipid metabolism |
| C00157 | 4.96 | 580.3945 | C10H18N08PR2 | up | Phosphatidylcholine | Arachidonic acid metabolism |
| C00157 | 4.96 | 580.3945 | C10H18N08PR2 | up | Phosphatidylcholine | Linoleic acid metabolism |
| C00157 | 4.96 | 580.3945 | C10H18N08PR2 | up | Phosphatidylcholine | alpha-Linolenic acid metabolism |
| C00157 | 4.96 | 580.3945 | C10H18N08PR2 | up | Phosphatidylcholine | Metabolic pathways |
| C00157 | 4.96 | 580.3945 | C10H18N08PR2 | up | Phosphatidylcholine | Retrograde endocannabinoid signaling |
| C00157 | 4.96 | 580.3945 | C10H18N08PR2 | up | Phosphatidylcholine | Choline metabolism in cancer |
| C04483 | 3.33 | 391.2854 | C24H40O4 | down | Deoxycholic acid | Bile secretion |
| C11133 | 2.35 | 445.1907 | C24H30O8 | up | Estrone glucuronide | Steroid hormone biosynthesis |
| C01921 | 2.83 | 464.3029 | C26H43NO6 | up | Glycocholic acid | Primary bile acid biosynthesis |
| C01921 | 2.83 | 464.3029 | C26H43NO6 | up | Glycocholic acid | Metabolic pathways |
| C01921 | 2.83 | 464.3029 | C26H43NO6 | up | Glycocholic acid | Bile secretion |
| C05980 | 5.13 | 483.2734 | C13H18O17P2R2 | up | Cardiolipin | Glycerophospholipid metabolism |