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. Author manuscript; available in PMC: 2022 Jun 16.
Published in final edited form as: DNA Repair (Amst). 2019 Feb 5;76:1–10. doi: 10.1016/j.dnarep.2019.02.003

Figure 1:

Figure 1:

POF implicated mutations mapped onto the A) primary sequences of MCM8 or MCM9 with indicated domains and motifs for each. Structural homology models shown in ribbon of B) MCM8 or C) MCM9 modelled from the most closely related yeast MCM2 subunit (PDBID:3JA8) with POF mutations mapped as indicated. D) Predicted quaternary homology model of the heterohexameric structure of MCM8/9 built upon the yeast MCM2–7 complex.