Table 1:
Replication/Recombination Helicases
| E. coli | S. cerevisiae | X. laevis / H. sapiens | |
|---|---|---|---|
|
| |||
| Fork Progression | DnaB | MCM2–7 | MCM2–7 |
| Rep | Pif1, Rrm3 | Pif1 | |
| RecQ | RecQL4, RecQL5 | ||
| PriA | FancJ, RTEL | ||
| Mph1 | FancM | ||
| MCM8, MCM9 | |||
|
| |||
| Fork Reversal | SMARCAL1*, ZRANB3* | ||
| HTLF* | |||
| RecG | Sgs1 | BLM, WRN | |
| UvrD | Srs2 | FBH1 | |
| Mph1 | FancM | ||
| MCM8, MCM9 | |||
|
| |||
| Fork Protection | FancJ, FancM | ||
|
| |||
| Fork Restart | RecQ | Sgs1 | RecQL1 |
| FancJ | |||
|
| |||
| Resection | RecQ | Sgs1 | BLM, WRN |
| UvrD | Srs2 | FBH1 | |
| DNA2 | DNA2 | ||
| RecBCD | |||
| FancJ | |||
| MCM8, MCM9 | |||
|
| |||
| Synapsis | Sgs1 | RecQL1, BLM, RecQL5 | |
| FancJ, RTEL1 | |||
| UvrD | Mph1 | FBH1 | |
| MCM8, MCM9 | |||
| Mer3 | HFM1, HelQ | ||
|
| |||
| Branch Migration | RecG, RecQ | Sgs1 | RecQL1, BLM, WRN |
| RuvAB | |||
|
| |||
| Dissolution | RecQ | Sgs1 | BLM |
*
translocase