Table 1:

Simulation results: percent of selecting good, best or toxic dose, for the proposed CR-CRM design compared to benchmark performances and Wages and Tait’s design (W&T). Simulated trials with targeted maximum toxicity = 25% and N = 35 + 35. (n/a : not applicable)

					Probability of picking (percent)
Scenario	MTD	Good	Best	Method	Good dose	Best dose	Toxic dose
S1	3	2,3	3	CR-CRM	82	63	10
				Benchmark	90	81	10
				W&T	72	39	3
S2	3	1,2,3	1,2,3	CR-CRM	94	94	6
				Benchmark	99	99	1
				W&T	99	99	1
S3	3	2,3	2,3	CR-CRM	92	92	6
				Benchmark	98	98	2
				W&T	86	86	2
S4	3	2,3	3	CR-CRM	93	69	4
				Benchmark	100	91	0
				W&T	83	42	1
S5	1	1	1	CR-CRM	91	91	9
				Benchmark	87	87	13
				W&T	56	56	4
S6	1	1	1	CR-CRM	95	95	5
				Benchmark	97	97	3
				W&T	80	80	2
S7	2	2	2	CR-CRM	76	76	8
				Benchmark	89	89	3
				W&T	73	73	3
S8	1	1	1	CR-CRM	91	91	9
				Benchmark	90	90	10
				W&T	70	70	6
S9	5	4,5	5	CR-CRM	93	72	n/a
				Benchmark	100	91	n/a
				W&T	40	18	n/a
S10	5	3,4,5	3,4,5	CR-CRM	100	100	n/a
				Benchmark	100	100	n/a
				W&T	77	77	n/a
S11	5	5	5	CR-CRM	80	80	n/a
				Benchmark	93	93	n/a
				W&T	25	25	n/a
S12	2	2	2	CR-CRM	71	71	9
				Benchmark	83	83	8
				W&T	63	63	5