Table 1.
Patient characteristics.
| Clinical variables | Number (n = 354) | Percentage (%) |
|---|---|---|
| Gender (Male/female) | 302/52 | 85/15 |
| Age (years, median) | 54 (20–77) | |
| Site | ||
| Oropharynx | 181 | 51.1 |
| Hypopharynx | 75 | 21.2 |
| Larynx | 98 | 27.7 |
| T stage | ||
| T1, T2 | 89 | 25.1 |
| T3, T4 | 265 | 74.9 |
| Clinical node(cN) | ||
| cN+ | 264 | 74.6 |
| cN− | 90 | 25.4 |
| Radiological positive node(rN) | ||
| rN+ | 244 | 69 |
| rN− | 110 | 31 |
| Radiological extranodal extension(rENE) | ||
| rENE+ | 140/244 | 57.4 |
| rENE− | 104/244 | 42.6 |
| Response | ||
| CR | 204 | 57.6 |
| PD | 24 | 6.8 |
| IR (SD + PR) | 126 | 35.6 |
| Status | ||
| Alive | 208 | 58.8 |
| Deaths | 146 | 41.2 |
| Deaths | ||
| Death due to disease | 117/146 | 80.1 |
| Death due to other cause (drug toxicity, second primary, tuberculosis, and unknown) | 29/146 | 19.9 |
| Histopathological differentiation | ||
| WDSCC | 2 | 0.6 |
| MDSCC | 65 | 18.3 |
| PDSCC | 107 | 30.2 |
| SCC not specified | 180 | 50.9 |
| Recurrence | ||
| Present | 158 | 44.7 |
| Absent | 196 | 55.3 |
| Recurrence site | ||
| Local | 58 | 36.7 |
| Nodal | 35 | 22.2 |
| Distant | 33 | 20.9 |
| Combination | 32 | 20.3 |
CR, complete response; PR, partial response; PD, progression of disease; SD, stable disease; IR, incomplete response; WDSCC, well-differentiated squamous cell carcinoma; MDSCC, moderately differentiated squamous cell carcinoma; PDSCC, poorly differentiated squamous cell carcinoma; SCC, squamous cell carcinoma.