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. 2022 Jun 15;17(1):641–658. doi: 10.1515/biol-2022-0067

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© 2022 Edeke Affiong Asuquo et al., published by De Gruyter

This work is licensed under the Creative Commons Attribution 4.0 International License.

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Micrographs of liver sections of experimental animals. (a) Liver sections of the control group showed normal histomorphology in experimental animals. (b) Liver sections of the induced but untreated group show histomorphological changes consistent with severe macrovesicular and microvesicular steatosis. (c) Liver sections of the standard-drug-treated group showed hepatocytes with multiple lipid vacuoles in their cytoplasms (white arrow). (d) Section of the liver of animals treated with SMF 30% showed normal histomorphology. (e) The group treated with 30% SAF showed mild microvesicular steatosis and intracytoplasmic lipid vacuoles. (f) Animals treated with SAF 15% + SMF 15% showed very mild microvesicular steatosis (white arrow) and large intracytoplasmic lipid vacuoles in the liver. The photomicrographs were taken using a Motic™ 9.0-megapixel microscope camera at ×400 magnification. H & E, ×400. The scale bar represents 10 mm.