Table 4.
Comparative Analysis of Sociodemographic, Clinical Features, Metabolic Status, and Psychiatric Disorders of Patients with Less Than 45, 45 to 65, and More Than 65 Years
| Variable | <45 Years n=444 | 45 - 65 Years n=1326 | >65 Years n=183 | p |
|---|---|---|---|---|
| Age in years, median (IQR) | 38 (34–42) | 54 (50–59) | 67 (66–69) | 0.0001 |
| Female sex, n (%) | 205 (46) | 757 (57) | 108 (59) | 0.0001 |
| School years, median (IQR) | 16 (12–16) | 13 (9–16) | 12 (9–16) | 0.0001 |
| Years of T2D diagnosis, median (IQR) | 0 (0–2) | 1 (0–3) | 2 (0–3) | 0.0001 |
| HbA1c%, median (IQR) | 8.6 (6.6–10.9) | 7.7 (6.4–10.1) | 7 (6.2–8.8) | 0.0001 |
| Total-cholesterol g/dL, median (IQR) | 180 (158–205) | 186 (160–214) | 184 (161–212) | 0.0217 |
| LDL-cholesterol g/dL, median (IQR) | 113 (89.5–133) | 116 (93–138) | 114 (90–137) | 0.0485 |
| HDL-cholesterol g/dL, median (IQR) | 40 (35–46) | 43 (37–50) | 44 (38–52) | 0.0001 |
| Non-HDL cholesterol g/dL, median (IQR) | 139 (116–164) | 143 (116–168) | 138 (111–163) | 0.1203 |
| Triglyceride g/dL, median (IQR) | 181 (128–265) | 170 (123–232) | 148 (115–195) | 0.0001 |
| Body mass index kg/m2, median (IQR) | 29.5 (26.05–33.85) | 29.05 (26.1–32.1) | 28.4 (25.2–32) | 0.0006 |
| Non-psychotic psychiatric disorders, n (%) | 221 (49) | 523 (39) | 40 (22) | 0.000 |
| Anxiety disorders, n (%) | 129 (29) | 263 (20) | 24 (13) | 0.000 |
| Affective disorders, n (%) | 114 (26) | 249 (19) | 20 (10.9) | 0.000 |
| Eating disorders, n (%) | 146 (33) | 319 (24) | 18 (10) | 0.000 |
| Hypoglycemic drugs, n (%) | ||||
| 0 | 102 (23) | 254 (19) | 28 (15) | 0.119 |
| 1 | 219 (49) | 620 (47) | 102 (56) | |
| 2 | 113 (25) | 409 (31) | 48 (26) | |
| 3 | 9 (2) | 39 (3) | 5 (3) | |
| 4 | 1 (0.2) | 4 (0.3) | 0 | |
| Insulin use, n (%) | 52 (12) | 100 (7) | 21 (11) | 0.012 |
| Number of antihypertensive drugs, n (%) | ||||
| 0 | 395 (88.9) | 1001 (75.4) | 95 (51.9) | 0.000 |
| 1 | 35 (7.8) | 220 (16.5) | 57 (31.1) | |
| 2 | 9 (2) | 89 (6.7) | 24 (13.1) | |
| 3 | 4 (0.9) | 15 (1.1) | 7 (3.8) | |
| 4 | 1 (0.2) | 1 (0.07) | 0 | |
| Number of hypolipidemic drugs, n (%) | ||||
| 0 | 375 (84.4) | 1063 (80.1) | 138 (75.4) | 0.063 |
| 1 | 59 (13.2) | 203 (15.3) | 39 (21.3) | |
| 2 | 10 (2.2) | 58 (4.3) | 6 (3.2) |
Abbreviations: IQR, interquartile range; T2D, type 2 diabetes; HbA1c, glycated hemoglobin; LDL, low density lipoprotein; HDL, high-density lipoprotein; Non-HDL, non-high density lipoprotein.