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. 2022 Mar 29;107(7):1956–1964. doi: 10.1210/clinem/dgac176

Table 2.

Candidate biomarker information

No. tR/min m/z ppm Metabolites Formula Adduct format Discovery set (SG/G)
Obsd. Calcd Variance Fold change
1 0.76 148.9352 148.9328 16.11 2,2,2-Trichloroethanol C2H3Cl3O M + H b 1.14
2 0.91 84.0814 84.0813 1.19 1-Methylpyrrolinium C5H10N M + H a 0.67
3 0.92 148.0431 148.0432 0.68 Thiomorpholine 3-carboxylate C5H9NO2S M + H b 1.46
4 2.44 171.1129 171.115 12.27 2,4-Dimethyl-1-(1-methylethyl)-benzene C11H16 M + Na a 0.73
5 4.96 715.5158 715.5156 0.28 SM (18:0/14:0) C37H77N2O6P M + K b 0.64
6 6.4 508.3767 508.3767 0 LysoPC (18:0/0:0) C26H54NO6P M + H b 1.66
7 8.83 814.6362 814.6326 4.42 PE-NMe (18:1/22:1) C46H88NO8P M + H b 1.42
8 9.62 812.6004 812.5935 8.49 PC (18:0/18:0) C44H88NO7P M + K a 0.68
9 11.2 804.5509 804.5519 1.24 PC (18:2/18:2) C44H80NO8P M + Na b 2.97

Abbreviations: G, atherosclerosis index greater than 4; SG, atherosclerosis index of ischemic stroke greater than 4; SM, sphingomyelin.

a Significant difference P less than .05.

b Very significant difference P less than .01.