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. 2022 Jun 16;12:10146. doi: 10.1038/s41598-022-14427-z

Figure 14.

Figure 14

(A) The specific IgG1, and IgG2a antibodies in the immunized mice serum. The white part represents the control group and the black part represents the MEV group (P < 0.01). (B) The IgG2a/IgG1 ratio of the two groups (P < 0.01). (C) The level of sIgA in bronchoalveolar lavage fluid of the two groups (P < 0.01). (D) The number of T cells that can produce IFN-γ in respiratory lymph node specimens after antigen stimulation. (E) The representative ELISPOT spot diagram. SAG4 peptide and PBS were used as negative controls, ConA was used as a positive control, and HKRB51 was used as the experimental group. (F) The number of T cells that can produce IFN-γ in splenocytes specimens after antigen stimulation. (G) The representative ELISPOT spot diagram. One-way ANOVA was used for the Statistical Analysis. Data are shown as mean ± SD. P < 0.05 was considered statistically significant (**P < 0.01).