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. 2022 Jun 2;13:881063. doi: 10.3389/fphar.2022.881063

TABLE 5.

Demographic and clinical characteristics of inpatients with ASMs prescription for SUP.

Characteristics Total (n = 893) Appropriate (n = 496) Overprescription (n = 397) p-value
Age (years) 0.001
 Median (Q1, Q3) 45 (58, 70) 56 (45, 67.5) 61 (46, 73)
 ≤44 213 (23.8) 122 (24.6) 91 (22.9) <0.001
 45–64 357 (40.0) 223 (45.0) 134 (33.8)
 ≥65 323 (36.2) 151 (30.4) 172 (43.3)
Gender 0.725
 Female 449 (50.3) 252 (50.8) 197 (49.6)
 Male 444 (49.7) 244 (49.2) 200 (50.4)
Current smokers 0.342
 No 737 (82.5) 404 (81.5) 333 (83.9)
 Yes 156 (17.5) 92 (18.5) 64 (16.1)
Alcohol consumption 0.039
 No 790 (88.5) 429 (86.5) 361 (90.9)
 Yes 103 (11.5) 67 (13.5) 36 (9.1)
Occupational status <0.001
 Employed 255 (28.6) 105 (21.2) 150 (37.8)
 Unemployed 453 (50.7) 286 (57.6) 167 (42.1)
 Retired 185 (20.7) 105 (21.2) 80 (20.1)
Residence 0.009
 Rural 473 (53.0) 282 (56.9) 191 (48.1)
 Urban 420 (47.0) 214 (43.1) 206 (51.9)
Health insurance 0.143
 No 303 (33.9) 158 (31.9) 145 (36.5)
 Yes 590 (66.1) 338 (68.1) 252 (63.5)
Comorbidity conditions
 Hypertension 225 (25.2) 128 (25.8) 97 (24.4) 0.639
 Diabetes mellitus 111 (12.4) 58 (11.7) 53 (13.4) 0.456
 Coronary artery disease 130 (14.6) 55 (11.1) 75 (18.9) 0.001
 Osteoporosis 76 (8.5) 44 (8.9) 32 (8.1) 0.666
 Number of comorbidities 0 (0, 1) 0 (0, 1) 1 (0, 2) 0.003
 Complications 127 (14.2) 53 (10.7) 74 (18.6) 0.001
Concurrently used drugs
 Anticoagulants 531 (59.5) 279 (56.3) 252 (63.5) 0.029
 Antiplatelet agents 24 (2.7) 16 (3.2) 8 (2.0) 0.266
 Systemic corticosteroids 345 (38.6) 258 (52.0) 87 (21.9) <0.001
 NSAIDs 722 (80.9) 389 (78.4) 333 (83.9) 0.040
Number of drugs excluding PPIs <0.001
 Median (Q1, Q3) 19 (14, 28) 21 (15.5, 29) 16 (12, 25)
 6–14 263 (29.5) 102 (20.6) 161 (40.6) <0.001
 15–19 212 (23.7) 116 (23.4) 96 (24.2)
 20–28 217 (24.3) 141 (28.4) 76 (19.1)
 29–59 201 (22.5) 137 (27.6) 64 (16.1)
Length of hospital stay (days) 0.172
 Median (Q1, Q3) 10 (7, 16) 11 (8, 15) 10 (7, 16)
 3–7 230 (25.8) 111 (22.4) 119 (30.0) 0.011
 8–10 224 (25.1) 131 (26.4) 93 (23.4)
 11–16 244 (27.3) 152 (30.6) 92 (23.2)
 17–54 195 (21.8) 102 (20.6) 93 (23.4)

The data are presented as numbers (proportions) or the median (interquartile range). Bold values indicate a p-value <0.05.