Table 3.
Stepwise backward logistic regression analysis for the risk of CVD in COPD.
| Dependent: | OR (univariable) | OR (multivariable) | OR (final) |
|---|---|---|---|
| Gender (female) | 0.35 (0.24–0.52, p < 0.001) | 0.41 (0.24–0.67, p < 0.001) | 0.36 (0.23–0.56, p < 0.001) |
| Age, years | 1.04 (1.02–1.06, p < 0.001) | 1.04 (1.02–1.06, p < 0.001) | 1.04 (1.02–1.06, p < 0.001) |
| BMI, kg/m2 | 1.02 (1.00–1.05, p=0.055) | — | — |
| Leukocyte, 10 ^ 9 cells/L | 1.03 (0.97–1.11, p=0.339) | — | — |
| Neutrophil, 10 ^ 9 cells/L | 1.14 (1.01–1.28, p=0.029) | 1.22 (1.02–1.48, p=0.034) | 1.25 (1.04–1.49, p=0.015) |
| RDW, % | 1.31 (1.15–1.51, p < 0.001) | 1.19 (1.02–1.39, p=0.031) | 1.20 (1.03–1.40, p=0.022) |
| BUN, mg/dL | 1.05 (1.02–1.07, p < 0.001) | 0.99 (0.95–1.03, p=0.692) | — |
| LDH, U/L | 1.01 (1.00–1.02, p < 0.001) | 1.01 (1.00–1.02, p=0.007) | 1.01 (1.00–1.02, p=0.003) |
| UA, µmol/L | 1.00 (1.00–1.01, p < 0.001) | 1.00 (1.00–1.00, p=0.218) | 1.00 (1.00–1.00, p=0.075) |
| Creatinine, µmol/L | 1.02 (1.01–1.02, p < 0.001) | 1.00 (0.99–1.01, p=0.572) | — |
| GTT, U/L | 1.00 (1.00–1.01, p=0.030) | 1.00 (1.00–1.01, p=0.236) | — |
| Osmolality | 1.06 (1.02–1.09, p < 0.001) | 1.02 (0.97–1.06, p=0.521) | — |
| HbA1c, % | 1.42 (1.20–1.68, p < 0.001) | 1.29 (1.07–1.57, p=0.009) | 1.34 (1.12–1.62, p=0.002) |
| HDL, mmol/L | 0.42 (0.25–0.67, p < 0.001) | 0.76 (0.42–1.34, p=0.352) | — |
| NLR | 1.15 (1.01–1.30, p=0.034) | 1.02 (0.78–1.31, p=0.892) | — |
| SIRI | 1.26 (1.04–1.53, p=0.017) | 0.79 (0.52–1.20, p=0.269) | 0.78 (0.58–1.05, p=0.106) |
RDW: red cell distribution width. BUN: blood urea nitrogen. LDH: lactate dehydrogenase. UA: uric acid. GTT: gamma-glutamyl transferase. HbA1c: glycosylated hemoglobin. HDL: high-density lipoprotein. NLR: neutrophil count to lymphocyte count ratio. SIRI: systemic inflammation response index. OR: Odds ratio.